204

■Bio-mathematics, Statistics and Nano-Technologies: Mosquito Control Strategies

GLOSSARY

The definitions of some commonly-used special terms: related to immunity, and that of

some general epidemiological terms are given here:

Table 10.4: Glossary of definitions for commonly-used special terms in this chapter.

A

Distribution coefficient

ACT

Artemisinin based combination therapy

AUC

Area under the curve

a

Distribution rate constant

B

Elimination coefficient

B:P

Blood-plasma concentration ratio

BSA

Body surface area

β

Elimination rate constant

Cab

Drug concentration in the incoming arterial blood

Cl

Clearance

Cmax

Maximal plasma concentration

Cp

Plasma concentration

Cpreg

Plasma concentration in the fetoplacental compartment

Cpreg

Plasma concentration in the fetoplacental compartment

CYP

Cytochrome P enzyme, with different subclasses

D

Dose

Dchild

Dosage to a child

Dadult

Dosage to an adult

DHA

Dihydroartemether

EC50

50% of maximum achievable effect

Emax

Maximum achievable effect

F

Bioavailability

Ft

Fraction of drug absorbed at time t

GA

Gestational age

Ka

Absorption rate constant

K10

Elimination rate constant

K12

Rate constant from central to peripheral compartment

K21

Rate constant from peripheral to central compartment

Kpreg:P

Fetoplacental compartment:plasma partition coefficient

m

meters (hight)

MFA

Total degree of enzyme maturation

mo

Months (age)

P.

Plasmodium

FURTHER READING

See the references attached to this chapter or contact the authors directly.

To whom correspondence should be addressed:

Prof. Sveinbjorn Gizurarson,

Faculty of Pharmaceutical Sciences, School of Health Sciences,

University of Iceland, Hofsvallagata 53, 107 Reykjavik, Iceland

E-mail: [email protected], Phone: +354 898 0318.